Abstract
In the context of a constantly increased slow down out of motherhood and you can of an increase of your occurrence off premature ovarian failure, it’s of the finest interest so you’re able to discard an excellent predictive marker of your own lifetime of the newest virility windows. Unfortunately, current offered indicators out of ladies virility (hormones pricing or echography number away from small follicles) possess a bad predictive property value premature ovarian incapacity. Over the last a decade, specific studies have advised you to definitely telomere duration tends to be correlated with premature ovarian incapacity, nevertheless consequence of this research was inconsistent.
Relative to recommendations out of Preferred Revealing Activities to possess Clinical Product reviews and you will Meta-Analyses (PRISMA), that it medical breakdown of the fresh literary works picked knowledge researching telomere size or telomerase hobby for the granulosa cells and you may/or perhaps in leukocytes given that a premature ovarian incapacity marker. Read More Telomere size during the granulosa tissues and leukocytes: a possible marker from ladies fertility? A logical report on brand new literary works